Method of treatment
Oral antibiotics
Length of treatment
7–14 days
Further Actions
• Avoid sexual contact until treatment has been completed
• Current sexual partners may also require testing and/or treatment
• Follow-up testing (test of cure) may be recommended, particularly if symptoms persist or antibiotic resistance is suspected
• Follow all medication instructions carefully and complete the prescribed treatment course
Fees
£120 (£60 if you tested with us)
Locations
Journey Overview
#1 Request Medications
Request treatment by completing the Mycoplasma genitalium treatment questionnaire and providing details of your symptoms, previous testing, and any recent antibiotic use.
#2 Clinical Review
A clinician will review your questionnaire, symptoms, medical history, previous results, and any relevant antibiotic exposure before prescribing treatment.
If further discussion is needed, one of our specialists will contact you before treatment is arranged.
#3 Collect or Mail Treatment
Where clinically appropriate, treatment can either be collected from the clinic or posted to you discreetly.
#4 Further Actions
You should avoid sexual contact until treatment has been completed and any advised abstinence period has passed.
Current sexual partners may also require testing and/or treatment to reduce the risk of reinfection.
Follow-up testing may sometimes be recommended, particularly if symptoms persist or antibiotic resistance is suspected.
Eligibility
Best For
Individuals with a confirmed Mycoplasma genitalium diagnosis requiring treatment and follow-up management.
Pregnancy/Breastfeeding
Requires careful clinical assessment.
Prior/Repeat Use
Symptoms persist, reinfection, or antibiotic resistance/treatment failure.
Discuss if
Recent antibiotic use, previous treatment failure, medication allergies, persistent symptoms, or concerns regarding antibiotic resistance.
Patient Feedback
FAQs
Treatment for Mycoplasma genitalium usually involves carefully selected oral antibiotics guided by current resistance-aware treatment approaches.
Depending on previous antibiotic exposure, symptoms, and any available resistance testing, different antibiotic regimens may be recommended. Commonly used antibiotics may include azithromycin, doxycycline, or moxifloxacin.
It is important to take all medication exactly as prescribed, even if symptoms improve before treatment is completed.
It is recommended to inform current sexual partners and, in some situations, recent partners if you are being treated for Mycoplasma genitalium.
Partners may require testing and/or treatment to reduce the risk of reinfection and onward transmission.
Your clinician can advise you regarding partner management based on your individual situation.
Treatment for Mycoplasma genitalium is often effective, although success rates can vary depending on antibiotic resistance patterns.
Because resistant strains are increasingly common worldwide, some people may require alternative antibiotics or follow-up testing to confirm clearance.
Following treatment instructions carefully and attending any recommended follow-up testing helps improve treatment success.
Antibiotics used to treat Mycoplasma genitalium can sometimes cause side effects, although many people tolerate treatment well.
Possible side effects may include:
• Nausea
• Diarrhoea
• Abdominal discomfort
• Headache
• Dizziness
Rarely, allergic reactions or more serious side effects can occur. You should discuss any medication allergies or previous antibiotic reactions with your clinician before starting treatment.
Treatment during pregnancy requires careful clinical assessment because some antibiotics used for Mycoplasma genitalium are not recommended during pregnancy.
If treatment is needed, your healthcare provider will select an antibiotic considered safer during pregnancy, taking into account gestation, symptoms, and any available resistance information.
Currently, there are no effective home treatments for Mycoplasma Genitalium. It's important to seek professional medical treatment if you suspect you have this infection. Antibiotics are necessary to properly treat and clear the infection.
Symptoms may begin improving within days of starting treatment, although complete resolution can take longer in some cases.
It is important to complete the full prescribed course of antibiotics, even if symptoms improve earlier.
Follow-up testing may sometimes be recommended to confirm the infection has cleared.
Menopause itself doesn't directly influence the effectiveness of Mycoplasma Genitalium treatment, but changes in the vaginal flora during menopause can affect susceptibility to infections and their management. It's important to discuss any concerns with your healthcare provider, who can tailor the treatment to your specific needs.
If you still have symptoms after finishing your Mycoplasma Genitalium treatment, it's important to contact your healthcare provider. You may need additional testing or a different course of antibiotics if the infection hasn't been fully cleared or if there's resistance to the initial treatment.
Yes. Treatment failure can occur, particularly due to antibiotic-resistant strains or reinfection from an untreated partner.
If symptoms persist or repeat testing remains positive, additional assessment, resistance-guided treatment, or alternative antibiotics may be required.
Follow-up testing (often called a test of cure) may be recommended after treatment, particularly if symptoms persist, resistance is suspected, or reinfection risk is high.
Your clinician will advise whether repeat testing is needed and the most appropriate timing for this.
Sexual partners may also require testing and/or treatment, even if they have no symptoms.
This helps reduce the risk of reinfection and onward transmission.
Your clinician can advise on the most appropriate partner management approach.
Page last reviewed by Mrs Magdalena Nowacka on 25 May 2026 for general guidance only. It is not intended to replace the advice of your clinician.