Lymphogranuloma venereum (LGV) is a sexually transmitted infection caused by a particular strain of Chlamydia bacteria. LGV attacks the lymph nodes which play an important part in fighting infections. LGV is commonly associated with men who have sex with men (MSM), and is less common in women.
LGV is not routinely tested for in sexual health clinics. If you have tested positive for Chlamydia and your symptoms match up with those of LGV, a further test will be run by the lab to determine your LGV status.
You can read more about how LGV is tested here.
Symptoms
What are the symptoms of LGV?
LGV can sometimes be asymptomatic (does not produce symptoms), however, most individuals start to show symptoms within 3-30 days of being infected.
The most common symptoms that have been seen in the UK occur in the rectum. This includes bleeding, constipation, discomfort during bowel movements, pain, presence of pus, or the presence of an ulcer
In addition to that, swellings may occur in the lymph nodes and most commonly be felt in the armpits, groins and sometimes in the neck. They might be accompanied by pain, fever and sometimes a rash. There may be sores or ulcers in the gluteal or genital region which develop.
When do LGV symptoms start to appear?
The incubation period of the LGV causing pathogen is anywhere from 3 to 30 days after coming in contact with it. This means that the first symptom of the infection can occur anywhere from three days to one month.
What complications can LGV lead to, if untreated?
The good news is that if caught early, an LGV infection can be completely cured with the right antibiotics, as long as the course of the treatment is completed. However, if left untreated, there are several complications which may occur.
- Fistula: An abnormal “bridge” or connection is formed between the rectum and vagina
- Scarring and/or narrowing of the rectum (and genitals in general)
- Infections in liver, heart or joints
- Long term pain/swelling in groins
- Infertility (in women)
- Encephalitis (rare): This is a condition in which the infection spreads to the brain and inflammation of the organ occurs
Can you have LGV without any symptoms?
The Center for Disease Control and Prevention (CDC) states that asymptomatic rectal infections are possible and have been seen. On occasion there are also “self-limiting” sores that have been identified, in which case the infection stays limited to the area where the sores are present.
Causes
How do you get LGV?
LGV infection is caused by one of three serotypes of the bacteria Chlamydia trachomatis: either L1, L2, or L3. It is spread when an infected individual takes part in unsafe, unprotected anal, vaginal or oral intercourse.
What factors can increase the likelihood of getting LGV?
Transmission of LGV is higher in individuals who practice chemsex, group sex, anal fisting, and sharing unclean sex toys. It is important to understand that LGV cannot be passed on by kissing, sharing towels or toilet seats. When left untreated, LGV may cause lasting damage to the anus and rectum which may only be fixed using surgery.
Can I get LGV even if I wear a condom?
Barrier methods of birth control such as condoms, can greatly reduce the risk of passing or contracting LGV infections, however there is a risk that remains. Condoms are highly effective in preventing pregnancies and transmission of STIs, however there remains a small risk nonetheless.
Can you get LGV from kissing?
There is no concrete evidence to suggest that a person can get LGV from kissing.
How can I prevent getting LGV?
The best way to protect yourself against STIs, including LGV, is to engage in safe sexual practices. Avoid risky behavior, use protection and get routine testing at a sexual health clinic. It is ideal that individuals and every new partner they may have, get tested prior to sexual intercourse, as a precaution.
Think you might have LGV?
Tested positive for LGV?
Prognosis
What is the long term prognosis for someone who has LGV?
LGV infection can be cured if caught early, however if treatment is delayed permanent scarring or worsening of the infection can occur.
Once treated, am I immune from getting LGV again?
Getting the infection once doesn’t make you immune or protect you from it. You should always practice safe sex measures to prevent LGV and other sexually transmitted infections.
Is there anything I can do to prevent LGV from returning?
Use condoms, get frequent testing for STIs and practice safe sex.
Is there anything I can do to prevent LGV from transmitting?
You can prevent the transmission of LGV by wearing condoms, or covering sex toys with a new condom each time they are used. We recommend that you thoroughly clean and disinfect your sex toys after every use.
How can LGV affect me during pregnancy?
Whilst LGV in women is less common, it is not impossible. If you have tested positive for LGV and are pregnant, you must start treatment right away.
Rest assured, there are effective medications available and it is possible to prevent complications to you and your child.
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Reviewed by: Dr. Manoj Malu (Clinical Director) and Phillip Black
Written By: Shannon Abraham
Last reviewed date: 1 September 2022
Next review due: 1 September 2025
Whilst this content is written and reviewed by sexual health specialists, it is for general guidance only. It is not intended to replace the advice of your clinician.
References & Further Reading
- NHS: Lymphogranuloma Venereum (LGV) – Devon Sexual Health
- NHS: Lymphogranuloma venereum (LGV) – Illnesses & conditions
- Terrence Higgins Trust: LGV (lymphogranuloma venereum)
- SH.UK: About LGV, Symptoms, Diagnosis & Treatment
- CDC: Lymphogranuloma Venereum (LGV) – STI Treatment Guidelines
- NHS: Lymphogranuloma venereum (LGV) – Illnesses & conditions
- BASHH: Guidelines. Genital ulceration. LGV. 2013