Molluscum Contagiosum

vs Genital Warts

Discovering a new lump or bump in the genital area can understandably cause concern. These changes are common, and in most cases, they are benign and manageable. Two frequent causes are molluscum contagiosum and genital warts.

Although they may appear similar at first glance, they are caused by different viruses and may require different management approaches. Accurate diagnosis is important to ensure appropriate advice and treatment.

What is Molluscum Contagiosum?

Molluscum contagiosum is a viral skin infection caused by a member of the poxvirus family. In adults, genital lesions are usually transmitted through direct skin-to-skin contact, most commonly during sexual activity.

Typical features include:

  • Small bumps (usually 2–5 mm)
  • Firm, smooth, dome-shaped appearance
  • A small central indentation (known as umbilication)
  • Usually painless, though occasionally itchy or inflamed

The virus remains confined to the outer layer of the skin and does not cause internal illness in otherwise healthy individuals.

What are Genital Warts?

Genital warts are caused by certain low-risk types of the Human Papillomavirus (HPV). HPV is very common, and many sexually active adults will be exposed at some point.

Warts may appear as:

  • Flesh-coloured or greyish growths
  • Soft or textured (sometimes described as “cauliflower-like”)
  • Flat or slightly raised
  • Single lesions or clusters
  • Located on the penis, scrotum, vulva, perineum, or around the anus

Unlike molluscum, HPV can remain in the surrounding skin even after visible warts are removed, which means recurrence can occur.

Molluscum Contagiosum vs Genital Warts: Key Differences

Although both conditions can present as genital skin growths, they differ in cause, appearance, and long-term behaviour.

Feature Molluscum Contagiosum Genital Warts
Causative Agent Molluscum contagiosum virus (MCV), a poxvirus Human papillomavirus (HPV), usually low-risk types.
Appearance Small (2–5 mm), smooth, dome-shaped bumps with a central dimple (umbilication) Irregular, textured, or cauliflower-like growths; may also be flat and smooth; flesh-coloured or greyish
Incubation Period Usually 2–7 weeks, occasionally longer (up to several months) Typically, weeks to months after exposure; timing can be variable.
Transmission Primarily direct skin-to-skin contact. In non-genital settings, indirect spread via shared items has been described but appears less common in adults. Direct skin-to-skin contact, most commonly during sexual activity
Recurrence Usually self-limiting. Once lesions resolve, the immune system has typically cleared the infection. Recurrence is uncommon unless there is reinfection or ongoing local spread. HPV can persist in surrounding skin even after visible warts are removed. Recurrence can occur, particularly within the first year after treatment.
Diagnosis In most cases, diagnosis is made through clinical examination. Further investigation is rarely required unless the appearance is atypical. In most cases, diagnosis is made through clinical examination. Biopsy or additional tests are uncommon unless features are unusual.


How are they diagnosed?

In most cases, diagnosis is made through careful clinical examination.

Occasionally, if the appearance is atypical or uncertain, further assessment may be recommended. An accurate diagnosis helps avoid unnecessary treatment and ensures the most appropriate management plan.

Do They Need Treatment?

Not always.

Both molluscum contagiosum and genital warts may resolve naturally as the immune system responds. However, many patients choose treatment for reasons such as:

  • Cosmetic concerns
  • Discomfort
  • Reducing the risk of transmission
  • Diagnostic certainty

The decision to treat is individual and guided by clinical findings and personal preference.

Treatment Options: Restoring Your Skin Health

Management depends on the diagnosis, the number of lesions, the location, and the patient’s priorities.

Options may include:

  • Monitoring for natural resolution
  • Topical therapies (in selected cases)
  • Procedural removal

What is Hyfrecation?

Hyfrecation is a commonly used procedural treatment in genital dermatology. It uses controlled electrical energy to remove visible lesions with precision.

What to expect:

  • Local anaesthetic is used to minimise discomfort.
  • The procedure is performed in a clinic and is typically brief.
  • Some patients require one session, while others may need additional treatments depending on the number of lesions and response.
  • Mild redness or scabbing is expected during healing. Aftercare guidance is provided.

Procedural treatments remove visible lesions but do not alter the underlying immune response. New lesions can occasionally develop until immune clearance occurs.

Your Care Pathway

Sexual health forms an important part of overall well-being. If you are uncertain whether a lesion represents molluscum contagiosum, genital warts, or another benign condition, a structured assessment provides clarity and appropriate guidance.

Your appointment typically includes:

  1. Confidential Pre-Assessment:
    You may complete a secure online questionnaire in advance. Where appropriate, photographs can be submitted for preliminary review to help guide booking and preparation.
  2. Clinical Review:
    A specialist will review your medical history and examine the affected area to confirm the diagnosis. Management options will be discussed in detail, including the benefits, limitations, and potential risks.
  3. In-Clinic Care:
    If treatment is clinically appropriate and you choose to proceed, procedural options such as hyfrecation may be performed during the same visit. In some cases, monitoring or staged treatment may be recommended instead.
  4. Aftercare and Follow-Up:
    Clear written aftercare guidance is provided. Follow-up review is available if needed, particularly if new lesions develop or healing does not progress as expected.

When to Seek Review

Any new, changing, painful, or uncertain genital lesion should be assessed. While many skin changes are benign, examination ensures clarity and appropriate guidance.

If you have noticed changes and would like a professional opinion, a specialist consultation can provide reassurance and a clear management plan tailored to you.

Fees

Genital Dermatology Consultation - £150

Genital Dermatology Consultation + Main Procedure + Follow Up - From £550

Local anaesthetic (by injection or cream depending on the lesions) is also included in the price. The following conditions have fixed prices:

  • Fordyce Spots - Patch Test (£350) + Main Procedure (£750 penile and/or £750 shaft)
  • Pearly Penile Papules (PPP) - £750-1000
  • Vestibular papillomatosis - Patch Test (£350) + Main Procedure (£750)

 

Follow up (within 4 weeks) - 1x Included

By default, patients 1x follow up visit is included in the quote we offer you. In some complex cases, we may offer an additional follow up visit (this will be clarified in your quote/consultation).

Payment Options

Self Pay - by Cash/Card, but not American Express

Health insurance - via a self reimbursement policy

ClarePay/Klarna - a payment plan to split the cost over 4 payments.

Next Steps

Care In Clinic

Same day hyfrecation treatment for patients with a pre-appointment quote.

Care Online

Start or continue your care online.

Page last reviewed by Mrs Magdalena Nowacka on 21 January 2026 for general guidance only. It is not intended to replace the advice of your clinician.