16S rRNA Bacterial Gene Detection & Sequencing Test

Window Period

N/A

Biological Marker(s)

Ribonucleic Acid (RNA)

Potential Sample(s)

Blood, urine, respiratory secretions (such as sputum or nasal swabs) or tissue samples

Time for test results

7 working days

Locations

Fees

Journey Overview

The 16S rRNA Bacterial Gene Detection & Sequencing test is a diagnostic test that is used to identify the specific type of bacteria causing an infection, especially when other tests return negative. The 16S rRNA Bacterial Gene Detection & Sequencing test uses polymerase chain reaction (PCR) to amplify and detect bacteria’s genetic material (RNA). It can identify the presence of bacterial RNA even at very low levels.

#1 Pre-Appointment Questionnaire

To ensure enough time to discuss any questions or concerns, we ask you to fill out a simple questionnaire before your appointment.

#2 Consultation

We will begin by assessing your medical & sexual history, any symptoms you may be experiencing and discuss any questions you may have.

#3 Sample Collection

If it is still appropriate to proceed with the 16S rRNA Bacterial Gene Detection & Sequencing test (and you would like to), we will require the appropriate swab.

#4 Dispense Medications (If Clinically Indicated)

Where clinically indicated, we are able to offer medications in the same appointment as your consultation whilst you wait for your bacterial culture results.

#5 Receive & Review Results

Once the results are ready, we will share your results by (secure) e-mail. After you have had a chance to review them, you can reach out to us for a complimentary follow up call to discuss the next steps. We will discuss whether additional testing or medications are needed and the logistics of going about this.

Patient Feedback

Eligibility

Best For

Identifying specific bacterial infections.

Pregnancy Considerations

Safe during pregnancy, but please inform clinician.

Menstrual Considerations

Safe during menstruation, but please inform clinician.

Recent Antibiotic Use/Retesting

Please discuss with your clinician.

Contra-indications

No specific contra-indications.

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Consult Your Clinician If...

Pregnant, taking medications/antibiotics, have test concerns.

Fees

Genital Dermatology Consultation

Specialist Nurse: £150 (included in tests)

Specialist Doctor: £150 (not included in tests)

16s rRNA Bacterial Gene Detection & Sequencing Test

£250

18s rRNA Fungal Gene Detection & Sequencing Test

£250

Bacterial Culture and Sensitivity Test

£150

Skin Scraping (e.g. For Scabies)

£200

Scabies Ink Test

£150

Payment Options

Self Pay - By Cash/Card, but not American Express

Health insurance

FAQs

About The Test

What is the 16S rRNA Bacterial Gene Detection & Sequencing test?

The 16S rRNA Bacterial Gene Detection & Sequencing test is a diagnostic test used to detect the presence of bacterial RNA in your body. It helps identify the specific type of bacteria causing an infection, especially when other tests return negative.

How does the 16S rRNA Bacterial Gene Detection & Sequencing test work?

The 16S rRNA Bacterial Gene Detection & Sequencing test test uses polymerase chain reaction (PCR) to amplify and detect bacteria’s genetic material (RNA). It can identify the presence of bacterial RNA even at very low levels.

When should I have the 16S rRNA Bacterial Gene Detection & Sequencing test?

Your clinician may recommend the 16S rRNA Bacterial Gene Detection & Sequencing test to determine the exact type of bacteria causing your infection. This test is commonly used for diagnosing bacterial respiratory infections, urinary tract infections, and other bacterial infections.

What samples can you use for the 16S rRNA Bacterial Gene Detection & Sequencing test?

The 16S rRNA Bacterial Gene Detection & Sequencing test can be performed on various types of samples, including blood, urine, respiratory secretions (such as sputum or nasal swabs), and tissue samples. The specific sample required depends on the suspected site of infection.

How do I prepare for my 16S rRNA Bacterial Gene Detection & Sequencing test?

Usually, there are no special preparations are required for the 16S rRNA Bacterial Gene Detection & Sequencing test. However, it is always a good idea to follow any instructions your clinician provides. Inform your clinician about any medications, antibiotics, or dietary supplements you are currently taking. Some medicines can affect the accuracy of the test results.

Are there any potential risks or complications associated with the 16S rRNA Bacterial Gene Detection & Sequencing test?

The 16S rRNA Bacterial Gene Detection & Sequencing test is a safe and low-risk test with no significant complications reported.

Can pregnant women safely undergo the 16S rRNA Bacterial Gene Detection & Sequencing test?

Pregnant women can safely undergo the 16S rRNA Bacterial Gene Detection & Sequencing test. It does not pose any specific risks to the mother or the baby. However, informing your clinician if you are pregnant or planning to become pregnant is always essential.

Can children undergo the 16S rRNA Bacterial Gene Detection & Sequencing test?

If a child needs to undergo the 16S rRNA Bacterial Gene Detection & Sequencing test, the sample collection process may vary depending on their age and cooperation levels. The clinician will be able to guide on the best approach for collecting the sample from the child.

What are the limitations of the 16S rRNA Bacterial Gene Detection & Sequencing test?

While it can be a useful tool in detecting bacterial infections, there is a possibility of false-positive or false-negative results.

False-positives can happen if the test detects bacterial RNA from non-pathogenic bacteria or if there is contamination during sample collection or processing.

False-negatives can occur if the amount of bacterial RNA in the sample is too low for the test to detect.

How long should I wait before having the 16S rRNA Bacterial Gene Detection & Sequencing test?

If you have recently taken antibiotics, it is recommended to wait at least 48 to 72 hours before having the 16S rRNA Bacterial Gene Detection & Sequencing test. Antibiotics can potentially interfere with the accuracy of the test, so it is important to give your body enough time to clear them from your system.

Is my 16S rRNA Bacterial Gene Detection & Sequencing test confidential?

Yes. Everything you share with us is confidential and will not be shared with the NHS or any other healthcare provider, including your GP unless you specifically ask us to do so.

About The Results

How will I receive my 16S rRNA Bacterial Gene Detection & Sequencing test results?

You can receive your 16S rRNA Bacterial Gene Detection & Sequencing test results by either text or email.

What precautions do I need to take whilst waiting for my 16S rRNA Bacterial Gene Detection & Sequencing test results?

While waiting for your 16S rRNA Bacterial Gene Detection & Sequencing test results, it is important to continue practicing good hygiene.

What do the results of my 16S rRNA Bacterial Gene Detection & Sequencing test mean?

A positive result indicates that the targeted bacteria was detected in your sample, which suggests an active infection.

A negative result means that the bacteria was not detected, indicating the absence of an active infection. Keep in mind that regardless of your test results, it’s important to continue practising good hygiene.

What happens if my 16S rRNA Bacterial Gene Detection & Sequencing test is positive?

Your clinician will arrange a follow-up call to discuss your treatment options. It is important to follow the advice given regarding further treatment and precautions to prevent the spread of the infection to others. Remember to continue practising good hygiene regardless of your test results.

Will medications I am currently taking affect my 16S rRNA Bacterial Gene Detection & Sequencing test results?

Medications you are currently taking should not affect the results of your 16S rRNA Bacterial Gene Detection & Sequencing test. However, it is always a good idea to inform your clinician about any medications you are taking, as they can provide specific instructions or considerations based on your situation.

Will I need to repeat the 16S rRNA Bacterial Gene Detection & Sequencing test?

Whether or not you will need to repeat the test will depend on your individual circumstances. Your clinician will consider factors such as your symptoms, medical history, and initial test results to determine the best course of action.

Next Steps

Page last reviewed by Mrs Magadelana Nowacka on 19 January 2024 for general guidance only. It is not intended to replace the advice of your clinician.