Dosage Timeline (normal schedule)
Dose 1: Day 0 (as recommended)
Dose 2: 1 month after the first dose
Dose 3: 6 months after the first dose
Dosage Timeline (accelerated schedule)
Recommended for people who need rapid protection, such as those at higher risk of exposure.
Dose 1: Day 0
Dose 2: 7 days after your first dose
Dose 3: 21 days after your first dose
Dose 4: 12 months after your first dose to provide long-term protection
Possible Side Effects
Pain and potential bruise at the injection site, headaches, tiredness, nausea and generally feeling unwell for up to 3 days post injection.
Locations
Fees
£70 per dose (3 doses in total)
Initial consultation fee applies for new patients.
Journey Overview

The Hepatitis B vaccine is a vaccine that prevents Hepatitis B infection. To be fully protected you will need to receive 3 doses of this vaccination at recommended intervals. The immunity will start to develop after the first dose but it takes a full course (3 doses) for the body to develop optimum protection.
When you start having the vaccines the body begins to develop antibodies, if you are exposed to the virus in the future you are capable of fighting it off so that you do not become unwell.
#1 Book an Appointment
To help us prepare and allow time for discussion, you will be asked to complete a short medical questionnaire before your appointment.
#2 Initial Consultation (If First Visit)
We will review your medical and relevant sexual history, assess any symptoms, and answer any questions you may have.
#3 Administer 1st Dose
If appropriate to proceed, the Hepatitis B vaccine will be administered during your appointment.
#4 Administer 2nd Dose
The second dose should be administered 1 month after your first dose.
#5 Administer 3rd Dose
The third dose should be administered 6 months after your second dose to complete the vaccination course.
Patient Feedback
Eligibility
Best For
Individuals at increased risk, such as healthcare workers, people with multiple sexual partners, and travellers to regions where the virus is common.
Pregnancy/Breastfeeding
Safe during pregnancy and breastfeeding.
Menstruation
You can safely receive the Hepatitis B vaccine at any point during your menstrual cycle.
Prior/Repeat Use
Our Specialists recommend booster doses only for specific groups (e.g. those at ongoing occupational risk or with impaired immunity), in accordance with national guidance. Or, if a previous vaccination course was left incomplete, ensuring your continued protection.
Do NOT use if
Avoid the vaccine if you have an allergy to its components, had a previous severe reaction, or are currently unwell with a high temperature.
Avoid/Discuss if
Discuss with our Specialists if you have severe allergies to yeast or previous doses, or if you are currently unwell with a high temperature.
FAQs
We offer a complete Hepatitis B vaccination course to help protect against Hepatitis B infection. The standard schedule is three doses over six months, with accelerated schedules available if faster protection is needed.
Before vaccination, a blood test may be recommended to check your immunity or rule out an existing infection. If appropriate, a follow-up blood test can be arranged after completing the course to confirm you have developed protective antibodies.
If you think you have been exposed to Hepatitis B in the last few days, seek medical advice promptly, as you may need post-exposure treatment rather than vaccination alone.
No. Receiving the Hepatitis B vaccine is a personal health decision, and there is no medical requirement to tell your current or previous partners.
Some people choose to discuss vaccination as part of conversations about sexual health, especially if it encourages partners to check their own vaccination status or consider testing. If you are receiving the vaccine following a recent exposure, it may also be appropriate to let the partner involved know so they can seek medical advice.
The Hepatitis B vaccine is highly effective. More than 95% of healthy people develop long-term protection after completing the full vaccination course.
Protection is usually long-lasting, and most people do not need a booster once they have developed adequate immunity. For people at higher risk of exposure, a follow-up blood test may be recommended to confirm the vaccine has been effective.
Most side effects are mild and resolve within a few days.
Common side effects include:
• Soreness, redness, or swelling at the injection site
• Mild headache
• Tiredness
• A slight fever
Serious allergic reactions are very rare. If you develop symptoms of a severe allergic reaction, such as difficulty breathing or swelling of the face or throat, seek emergency medical attention immediately.
The Hepatitis B vaccine is safe to receive during pregnancy if you are at increased risk of infection. The vaccine itself and the dosing schedule are the same as for other adults.
Pregnant women in the UK are routinely screened for Hepatitis B during antenatal care. If you are at risk because of your work, travel, or personal circumstances, your healthcare provider can advise whether vaccination is recommended.
Protection develops gradually throughout the vaccination course. Many people develop some protection after the second dose, but the best protection is achieved after completing the recommended vaccination schedule. For most people, protective immunity develops within one to four months of the final dose. In some cases, a blood test may be recommended to confirm an adequate antibody response.
Completing the full course is important for long-term protection. If you need protection more quickly, an accelerated vaccination schedule may be available.
The Hepatitis B vaccine remains effective during menopause. However, immune responses can naturally become less robust with age.
Factors that may reduce the response include:
• Increasing age
• Smoking
• Higher body weight
• Diabetes
• A weakened immune system
If you are at higher risk of exposure, a follow-up blood test may be recommended to confirm you have developed adequate immunity.
The Hepatitis B vaccine prevents infection but does not treat an existing one.
If you develop symptoms such as jaundice, dark urine, severe tiredness, or abdominal pain after completing the vaccination course, you should arrange a medical assessment. These symptoms could indicate an infection that occurred before the vaccine became effective or another liver condition. Blood tests can determine the cause and whether further treatment is needed.
Yes. Approximately 5–10% of healthy adults do not develop a protective antibody response after the primary vaccination course.
A blood test performed one to four months after the final dose can check whether you have developed immunity. If antibody levels are low, an additional vaccine dose or a repeat vaccination course may be recommended.
People who remain unprotected after repeat vaccination should seek urgent medical advice after any potential exposure, as they may need Hepatitis B immunoglobulin (HBIG) for temporary protection.
A follow-up blood test may be recommended one to four months after your final vaccine dose to confirm you have developed protective antibodies.
This is particularly important for people at higher risk of exposure, such as healthcare workers or those with certain medical conditions. If your antibody levels are low, additional vaccination may be recommended.
It depends on your partner's immunity and whether they have been exposed to Hepatitis B.
If your partner has not previously been vaccinated or is not immune, vaccination may be recommended. Following a recent exposure, they should seek medical advice promptly, as they may need both vaccination and, in some cases, Hepatitis B immunoglobulin (HBIG).
A blood test can determine whether your partner is already protected or requires vaccination.
Page last reviewed by Mrs Magdalena Nowacka on 06 August 2026 for general guidance only. It is not intended to replace the advice of your clinician.